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Plaquing efficiency of herpes simplex virus type 1 with a defined agar overlay

Y M Siddiqui1, M N al-Ahdal

  • 1Department of Biological and Medical Research, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.

The New Microbiologica
|January 1, 1993
PubMed

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Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...