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Bone loss, contraception and lactation

S Mehta1

  • 1Special Programme of Research, Development and Research Training in Human Reproduction World Health Organization, Geneva, Switzerland.

Acta Obstetricia Et Gynecologica Scandinavica
|April 1, 1993
PubMed
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Bone loss is a natural aging process, particularly in women, leading to osteoporosis and fractures. Peak bone mass and postmenopausal bone loss rates significantly influence fracture risk.

Area of Science:

  • Gerontology
  • Endocrinology
  • Orthopedics

Background:

  • Bone mass loss is a universal aging phenomenon, more severe in women, leading to osteoporosis and fractures.
  • Osteoporosis prevalence is increasing with the aging global population.
  • Bone density peaks in the third decade and declines thereafter, influenced by genetics, lifestyle, and hormonal changes.

Purpose of the Study:

  • To review factors influencing bone loss and susceptibility to osteoporosis.
  • To examine the role of menopause and declining ovarian function in postmenopausal bone loss.
  • To assess the limited available data on steroid hormone contraceptive use and bone density.

Main Methods:

  • Literature review of factors affecting bone mineral density.
  • Analysis of age-related bone loss patterns.
Keywords:
Age FactorsBiologyCalciumContraceptionContraceptive Methods--beneficial effectsDemographic FactorsDeveloped CountriesDeveloping CountriesFamily PlanningFertilityIngredients And ChemicalsInorganic ChemicalsLactationLiterature ReviewMaternal PhysiologyMenopauseMetalsOral Contraceptives, Combined--beneficial effectsOral Contraceptives--beneficial effectsPhysiologyPopulationPopulation CharacteristicsPopulation DynamicsReproductionReproductive BehaviorRisk Factors

Related Experiment Videos

  • Examination of hormonal influences on bone metabolism.

    • Main Results:

    • Bone loss begins premenopausally, accelerating postmenopause due to decreased estrogen.
    • Peak bone mass and postmenopausal bone loss rate are key determinants of osteoporosis risk.
    • Data on steroid hormone contraceptives and bone density is scarce, primarily focusing on combined oral contraceptives and depot medroxyprogesterone acetate.

    Conclusions:

    • Osteoporosis is likely irreversible once fractures occur.
    • Understanding premenopausal bone loss factors is crucial for prevention.
    • Further research is needed on hormonal influences, including contraceptive use, on bone health.