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Related Experiment Videos

Pharyngitis associated with herpes simplex virus in college students

J A McMillan1, L B Weiner, A M Higgins

  • 1Department of Pediatrics, SUNY Health Science Center, Syracuse.

The Pediatric Infectious Disease Journal
|April 1, 1993
PubMed
Summary

Herpes simplex virus (HSV) pharyngitis is common in college students, presenting with symptoms like sore throat and lesions. Clinical diagnosis is challenging, often mimicking other infections like strep throat.

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Upper respiratory complaints are frequent in college health centers.
  • Herpes simplex virus (HSV) is a common viral pathogen.
  • Distinguishing viral pharyngitis from bacterial infections is crucial for appropriate treatment.

Purpose of the Study:

  • To determine the prevalence of herpes simplex virus (HSV) in college students presenting with upper respiratory complaints.
  • To describe the clinical presentation of HSV pharyngitis.
  • To compare HSV pharyngitis with other common causes of acute pharyngitis in this population.

Main Methods:

  • Throat swabs were collected from students with upper respiratory complaints over 16 months.
  • Cultures for viral, streptococcal, and Mycoplasma pneumoniae were performed.

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  • Immunofluorescent staining identified HSV type 1.
  • Clinical examinations and diagnoses were recorded.

    • Main Results:

    • Herpes simplex virus (HSV) was isolated from 5.7% of 613 patients.
    • HSV type 1 was the predominant strain.
    • Common symptoms included pharyngeal erythema, exudate, and vesicular lesions.
    • HSV pharyngitis was often misdiagnosed as other infections, including strep throat.

    Conclusions:

    • Herpes simplex virus (HSV) is a significant cause of pharyngitis in college students.
    • Clinical differentiation of HSV pharyngitis from other acute pharyngitis causes is difficult.
    • Further diagnostic evaluation may be needed for accurate diagnosis and management.