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Detection of human papillomavirus DNA in an ameloblastoma using the in situ hybridization technique
W F van Heerden1, E J van Rensburg, E J Raubenheimer
1Department of Oral Pathology and Oral Biology, Medical University of Southern Africa, Medunsa.
Abstract:
HPV type 18 DNA was identified in an intrabony ameloblastoma using radiolabelled in situ hybridization. The viral DNA was found in a verrucous lesion in a cystic area of the tumor. The absence of HPV DNA in other epithelial areas of the ameloblastoma is suggestive of a secondary infection. HPV is not considered to be an etiological factor in the pathogenesis of this ameloblastoma.