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Canine parvovirus

R V Pollock1, M J Coyne

  • 1SmithKline Beecham Animal Health, West Chester, Pennsylvania.

The Veterinary Clinics of North America. Small Animal Practice
|May 1, 1993
PubMed
Summary
This summary is machine-generated.

Canine parvovirus (CPV-2) remains a significant threat to young dogs, with maternal antibodies often hindering vaccination success. Effective treatment relies on supportive care, as the virus is now endemic in dog populations worldwide.

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Area of Science:

  • Veterinary Virology
  • Canine Infectious Diseases

Background:

  • Canine parvovirus (CPV-2) emerged in the late 1970s, rapidly becoming a widespread canine pathogen.
  • While initially epidemic, CPV-2 now predominantly affects dogs aged 1 to 6 months.

Purpose of the Study:

  • To review the epidemiology, diagnosis, and management of canine parvovirus enteritis.
  • To discuss the impact of viral evolution and maternal antibody interference on vaccination efficacy.

Main Methods:

  • Review of existing literature on canine parvovirus.
  • Analysis of diagnostic approaches and treatment strategies.

Main Results:

  • Maternal antibody interference is the primary cause of vaccine failure.
  • Continued molecular evolution of CPV-2 has limited practical clinical significance.

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  • Definitive clinical diagnosis is possible in severe cases; laboratory confirmation is often required.
  • Treatment is primarily supportive, focusing on good veterinary care.

    • Conclusions:

    • Canine parvovirus is endemic and cannot be eliminated from domestic or wild dog populations.
    • CPV-2 will continue to be a persistent challenge for veterinary practitioners indefinitely.