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Sulphidopeptide leukotrienes in asthma
Clinical Science (London, England : 1979)
|May 1, 1993
Summary
Sulfidopeptide leukotrienes are key mediators in asthma pathophysiology, causing bronchoconstriction and airway hyperresponsiveness. Leukotriene antagonists and 5-LO inhibitors show promise for managing chronic asthma.
Area of Science:
- Pulmonary Medicine
- Immunology
- Pharmacology
Background:
- Bronchial asthma involves complex pathophysiology with no single causative mediator.
- Substantial evidence implicates sulfidopeptide leukotrienes in asthma's development and progression.