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Ultrastructural pathology of eccrine sweat gland epithelial cells in globoid cell leukodystrophy
H H Goebel1, S Kimura, K Harzer
1Division of Neuropathology, University of Mainz, Germany.
Journal of Child Neurology
|April 1, 1993
Abstract:
Three of four children were recognized by deficient beta-galactocerebrosidase activities as having globoid cell leukodystrophy inclusions in sweat gland epithelial cells, similar in ultrastructure to those seen in Schwann cells. This observation in globoid cell leukodystrophy emphasizes the need to include sweat gland epithelial cells in examinations of skin in globoid cell leukodystrophy, as well as in any neurometabolic disorder.