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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
Published on: December 17, 2010
[Senator's neuromyositis associated with Hashimoto's thyroiditis]
L Defebvre1, J J Hauw, A Destee
1Service de Neurologie A., C.H.R.U., Lille.
Abstract:
The concept and even the reality of Senator neuromyositis are discussed. One case is reported confirming its reality. The diagnosis is based on clinical signs (polymyositis and peripheric neuropathy), biological (muscular enzymes increase) and electrophysiological disturbances (myogenic syndrome, decrease of nerve conduction velocities), and histological lesions (polymyositis and denervation). The association with a Hashimoto thyroiditis could support the hypothesis of an autoimmune mechanism in the neuromyositis pathogenesis.
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