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Updated: Jul 29, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
The use of particulate hydroxyapatite and plaster of Paris in aesthetic and reconstructive surgery
N G Georgiade1, J Hanker, S Levin
1Division of Plastic, Maxillofacial and Reconstructive Surgery, Duke University Medical Center, Durham, North Carolina.
Abstract:
The authors describe their early investigative results of using a mixture of hydroxyapatite (HA) and plaster of Paris (PP) in skull and frontal sinus defects in a large series of cats. Histologically, bone was found to form and infiltrate the HA-PP implant over a period of months, with gradual resorption of the plaster in 6-8 weeks. Clinically, the HA-PP combination has been used in 24 patients over the past seven years for various skull, zygomatic, and mandibular defects.

