Promoter activity of the 1731 Drosophila retrotransposon in a human monocytic cell line

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Updated: Oct 2, 2026

Production of Replication-Defective Retrovirus by Transient Transfection of 293T cells
09:40

Production of Replication-Defective Retrovirus by Transient Transfection of 293T cells

Published on: December 4, 2007

S Codani-Simonart1, J Lacoste, M Best-Belpomme

  • 1UA CNRS 1135, Groupe de Génétique Cellulaire et Moléculaire, Université P. et M. Curie, Paris, France.

FEBS Letters
|July 5, 1993
PubMed

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The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
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