[Liver microcirculative disturbance in schistosomiasis portal hypertension]

Using reing resin vascular casts, ink perfusion, VG and electron microscope. We studied the liver microcirculative disturbance in rabbits (n = 20) and mice (n = 10) with chronic schistosomiasis. The results showed a decrease in the liver sinusoid number, tortuosity of the terminal branches of the portal vein, formation of a basement membrane in the space of Disse, capillarization of the sinusoid. These results suggest that liver microcirculative disturbance can contribute to schistosomiasis portal hypertension.