[Contributive factors of intellectual disorders in epileptic patients]

Fifty-two patients with primary epilepsy of tonic-clonic seizure type, whose CT scans were negative, were examined by Wechsler adult intelligence scale-revised (WAIS-RC). Full intelligence quotient (FIQ) of 26 patients were lower than normal. Multivariate analysis of variance (MANOVA) was done to analyze the influence factors of FIQ. The result demonstrated that there was a negative correlation between FIQ and seizure frequency, epileptic course, antiepilepsy drugs (P < 0.05). FIQ was not correlated with onset ages and electroencephalography changes (P > 0.05).