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S-adenosylmethionine metabolism in herpes simplex virus type 2-infected cells
C Seivwright1, J C Macnab, R L Adams
1Department of Biochemistry, University of Glasgow, U.K.
The Journal of General Virology
|July 1, 1993
Abstract:
Infection of primary rat embryo cells with herpes simplex virus type 2 has previously been reported to produce a dramatic and rapid inhibition of cellular DNA methylation. However, it has neither an immediate effect on S-adenosylmethionine breakdown nor on the relative pool sizes of S-adenosylmethionine and S-adenosylhomocysteine.