Related Experiment Video
Updated: Aug 4, 2026

The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects
Published on: October 2, 2014
[Digital subtraction angiography with carbon dioxide in severe arterial ischemia and allergy to iodinated compounds]
J Calvo Cascallo1, N Mundi Salvadó, M Cardona Fontanet
1Unidad de Angiología y Cirurgía Vascular, Hospital Cruz Roja de Barcelona, España.
Insights
Digital subtraction angiography using carbon dioxide (DIVAS-CO2) is a safe alternative for patients with chronic arterial ischemia when contrast arteriography is contraindicated. This technique provides good images for treatment planning.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Medical Imaging
Background:
- Chronic arterial ischemia (III or IV degrees) often requires surgical intervention (direct arterial surgery or endoluminal surgery).
- Contrast arteriography is contraindicated in patients with severe renal failure, heart failure, hyperthyroidism, or contrast agent hypersensitivity.
- Alternative imaging modalities are needed for patients with contraindications to contrast agents.
Abstract:
When in some selected patients, a direct arterial surgery (DAS) procedure or an endoluminal surgery (ES) are required for a chronic arterial ischemia (III or IV degrees), and an arteriography with contrast is absolutely contraindicated (because of severe renal failure without hemodialysis program or a severe congestive heart failure or a hyperthyroidism or a seriously demonstrated hypersensibility against the contrast agents); an angiography by digital subtraction with carbon dioxide (DIVAS-CO2) is indicated. This technique provides good quality images with minimal risks for the patient and an adequate study for ulterior treatment. We report a case of a 67-years-old woman, with diabetes-II, ischemic cardiopathy, arterial hypertension and a demonstrated hypersensibility against the iodide compounds. The patient was admitted because of a chronic ischemia (IV degree) with ischemic ulcerations on some fingers from the left foot. High doses of analgesic drugs were needed. Because the hypersensibility against the iodide compounds, an angiography with CO2 was carried out. The good quality images provided by this technique showed the factibility of a revascularization.
Related Concept Videos
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies for Cardiovascular System V: CT
Cardiac Catheterization I: Pre-Procedure Overview
Acute Coronary Syndrome III: Diagnostic Studies
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

