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Cloning and characterization of the Haemophilus influenzae mutB gene

J H Stuy1, R B Walter

  • 1Department of Biological Sciences, Florida State University, Tallahassee 32306.

Journal of Bacteriology
|August 1, 1993
PubMed

Abstract:

The Haemophilus influenzae mutB+ gene complements Escherichia coli uvrD mutants. The E. coli uvrD+ gene complements H. influenzae mutB1 mutants.

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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

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