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Silica stone--development due to long time oral trisilicate intake
1Department of Surgery, Veterans General Hospital-Taipei, National Yang-Ming Medical College, Taiwan.
Scandinavian Journal of Urology and Nephrology
|January 1, 1993
Summary
Long-term use of trisilicate antacids may lead to silica urolithiasis, causing kidney stones. This case highlights the importance of considering silica stones in patients with recurrent renal colic and antacid history.
Area of Science:
- Nephrology
- Gastroenterology
- Mineralogy
Background:
- Recurrent renal colic can have various etiologies.
- Trisilicate antacids are commonly used for gastric discomfort.
- Silica urolithiasis is a rare form of kidney stone.
Observation:
- A 30-year-old female presented with a history of recurrent renal colic.
- She had a long-term history of consuming trisilicate-containing antacids.
- Standard diagnostic methods like intravenous pyelography and ureteroscopy failed to identify calculi.
Findings:
- Metabolic evaluations for common causes of kidney stones were normal.
- X-ray diffraction analysis confirmed the presence of a silicate stone.
- This finding suggests a link between antacid use and silica stone formation.
Implications:
- Clinicians should consider silica urolithiasis in patients with a history of long-term trisilicate antacid intake and recurrent renal colic.
- This case expands the differential diagnosis for unexplained kidney stones.
- Further research may be warranted to understand the prevalence and mechanisms of antacid-induced silica urolithiasis.