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Single-stranded genomic RNA from turkey enterovirus-like virus
C S Hayhow1, A V Parwani, Y M Saif
1Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Ohio State University, Wooster 44691.
Avian Diseases
|April 1, 1993
Summary
A novel enterovirus causing disease in young turkeys has been identified. Further analysis confirmed its classification as an enterovirus based on its physical and genetic properties.
Area of Science:
- Virology
- Avian Pathology
Background:
- A disease syndrome in young turkeys was previously linked to an enterovirus-like virus.
- Initial designation was based on size, morphology, and intracytoplasmic crystalline arrays.
Purpose of the Study:
- To further characterize the enterovirus-like virus.
- To definitively classify the etiological agent of the turkey disease syndrome.
Main Methods:
- Buoyant density centrifugation in Cesium Chloride (CsCl).
- Analysis of viral genome size and type.
Main Results:
- The virus exhibited a buoyant density of 1.33 g/ml in CsCl.
- The viral genome was determined to be single-stranded RNA (ssRNA) of approximately 7.5 kilobases.
Conclusions:
- The combined characteristics strongly support the classification of the virus as an enterovirus.
- This finding clarifies the etiological agent responsible for the observed disease in turkeys.