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Neuron-specific enolase: a serum tumor marker in malignant germ-cell tumors?
1Urologische Klinik, Universitätsklinikum Eppendorf, Hamburg, FRG.
European Urology
|January 1, 1993
Abstract:
Neuron-specific enolase was determined in 100 patients with germ-cell tumors. An elevation was found in 5/18 patients with advanced seminoma and in 7/25 patients with advanced nonseminoma. Including all tumor stages of both seminoma and nonseminoma, we found less than 20% NSE-positive patients. Some of these showed false-positive or false-negative results during follow-up examinations. NSE does not seem to be a valuable tumor marker in germ-cell tumors.