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Five different histological subtypes of germ cell malignancies in an XY female
G L Bremer1, J A Land, A Tiebosch
1Department of Obstetrics and Gynecology, University Hospital, Maastricht, The Netherlands.
Gynecologic Oncology
|August 1, 1993
Abstract:
A case of a 19-year-old female with 46 XY gonadal dysgenesis and five different histological subtypes of germ cell malignancies is described. Both adnexa were removed, preserving the uterus. Pathology revealed gonadoblastoma with dysgerminoma differentiation present in both gonads and in the left gonad mature teratoma, embryonal carcinoma, and endodermal sinus tumor were identified as well. She received no adjuvant treatment and has remained well 30 months after diagnosis.