Related Experiment Video
Updated: Aug 6, 2026

Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
[CD23: structures, functions and practical perspectives in allergy reactions]
1Département de pédiatrie, pavillon S, hôpital E-Herriot, Lyon, France.
Abstract:
CD23, the low-affinity receptor for IgE, is a surface cell marker and surface CD23 is cleaved into soluble fragments by an autocatalytic mechanism. cDNA clone encoding for CD23 has been isolated and structural studies realized. CD23 is expressed by B and T lymphocytes and by other cells including tumor cells. IL4 and IgE are the most potent inducer of CD23 expression. CD23 has multiple functions: B cell growth and differentiation, capacity to present antigen, cellular mobility, inflammation... The serum sCD23 level is often increased in allergic patients.
Related Concept Videos
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Cross-reactivity
Allergic Reactions
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Allergic Drug Reactions
B Cell Activation and Differentiation
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...

