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Synthesis and antimicrobial properties of S-substituted derivatives of 2-thiouracil
E Wyrzykiewicz1, G Bartkowiak, Z Nowakowska
1Instytut Roślin i Przetworów Zielarskich, Poznań, Polska.
Farmaco (Societa Chimica Italiana : 1989)
|July 1, 1993
Abstract:
The synthesis of 24 new 2-alkylthio and 2-(E)-N-thioalkyl-4-azachalkonyl substituted derivatives of uracil and their antimicrobial activity are reported. In particularly compounds 6o and 6p showed a good antibacterial activity against Staphylococcus aureus and Streptococcus faecalis.