Related Experiment Videos
Glomerular basement membrane abnormalities in infants with heavy proteinuria
K P Mehta1, U S Ali, A R Chitale
1Department of Paediatrics, Bai Jerbai Wadia Hospital for Children and Research Centre, Parel, Bombay, India.
Pediatric Nephrology (Berlin, Germany)
|August 1, 1993
Summary
Infantile nephrotic syndrome can present with glomerular basement membrane abnormalities, similar to Alport syndrome. These findings in non-familial cases suggest a need for further evaluation of early-onset proteinuria.
Area of Science:
- Nephrology
- Pediatric Nephrology
- Pathology
Background:
- Infantile-onset heavy proteinuria and nephrotic syndrome require precise diagnosis.
- Glomerular basement membrane (GBM) abnormalities are characteristic of Alport syndrome.
- Distinguishing between genetic and acquired causes of early-onset kidney disease is crucial.