Related Experiment Videos
Nutritional status and growth in children less than 12 kg treated with continuous ambulatory peritoneal dialysis
C Stefanidis1, H Michelakaki, A Koulieri
1A & P Kyriakou Children's Hospital, Athens, Greece.
Insights
Continuous ambulatory peritoneal dialysis (CAPD) improved nutritional status in children, but did not significantly enhance height or muscle mass over one year. Some children with initial height deficits showed improvement.
Area of Science:
- Pediatric Nephrology
- Nutritional Science
- Clinical Research
Background:
- Children with end-stage renal disease often experience malnutrition and growth failure.
- Continuous ambulatory peritoneal dialysis (CAPD) is a treatment option for pediatric patients with kidney failure.
- Assessing nutritional status and growth is crucial for managing children undergoing CAPD.
Purpose of the Study:
- To evaluate changes in nutritional status and growth parameters in children on CAPD.
- To determine the impact of CAPD on weight, body composition, and growth velocity.
- To identify factors influencing nutritional and growth outcomes in this pediatric population.
Main Methods:
- Longitudinal study of 13 children weighing less than 12 kg.
- Nutritional parameters (weight, skinfold, serum albumin, muscle circumference) assessed at baseline and 1 year.
- Height, protein intake, urea nitrogen appearance (UNA), and insulin-like growth factor levels were measured.
Main Results:
- Significant improvements observed in weight, triceps skinfold, and serum albumin after 1 year of CAPD.
- No significant changes in overall height or midarm muscle circumference.
- Children with initial abnormal height (<--2 SDS) showed significant height improvement.
- Protein intake and UNA remained unchanged, but a correlation between them was noted.
Conclusions:
- CAPD can improve key nutritional markers in pediatric patients.
- Long-term CAPD may not significantly enhance linear growth or muscle mass in all children.
- Monitoring specific growth parameters and nutritional intake is essential for optimizing CAPD therapy in children.
Abstract:
Various parameters of nutritional status and growth in 13 children with weight less than 12 kg were estimated at the start of continuous ambulatory peritoneal dialysis (CAPD) and 1 year later. A significant improvement in weight, triceps skinfold, and serum albumin was noticed. Height and midarm muscle circumference did not change significantly. However, a significant improvement in height occurred in patients with initial abnormal height (<--2 SDS). There was no significant change in protein intake and urea nitrogen appearance (UNA) during the study period. A significant correlation between protein intake and UNA was noticed. All patients had normal serum insulinlike growth factor. In conclusion, there was no significant change in either height velocity or muscle mass despite the improvement in many nutritional parameters.