Related Experiment Videos
A familial/genetic study of plasma serine and glycine concentrations
1Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242.
Biological Psychiatry
|August 15, 1993
Abstract:
Plasma serine and glycine concentrations were assayed in a sample of 28 nuclear families (n = 108). Complex segregation analysis of these familial data reveals significant genetic control of concentrations via a single major gene locus. The serine and glycine metabolizing enzyme serine hydroxymethyltransferase (SHMT) is suggested as the most likely candidate for this single major gene locus.