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Updated: Aug 5, 2026
08:55
Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
Published on: August 7, 2018
Visualization of intracellular calcium during necrotaxis
E Constant1, A Le Negrate, A de Boisfleury-Chevance
1Centre d'Ecologie Cellulaire, Hôpital de la Salpétrière, Paris, France.
Blood Cells
|January 1, 1993
Abstract:
Granulocytes are known to exhibit positive chemotaxis towards erythrocytes destroyed by laser irradiation (necrotaxis). A computerized method for visualizing intracellular calcium concentration in granulocytes during necrotaxis has been developed. Successive bursts of fluorescence were observed: 1 degree) about 10 s after the creation of the necrotactic source; 2 degrees) when the granulocyte touched the target.
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