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Related Experiment Videos

Coagulation tests in predicting haemorrhage after prostatic resection

Z Ahsan1, R Cartner, P J English

  • 1Department of Urology, Dryburn Hospital, Durham.

British Journal of Urology
|August 1, 1993
PubMed
Summary
This summary is machine-generated.

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Simple coagulation tests, like prothrombin time, can predict excessive bleeding after transurethral resection of the prostate (TURP). Abnormal prothrombin time immediately post-surgery indicates a higher risk of significant post-operative hemorrhage in TURP patients.

Area of Science:

  • Urology
  • Hematology
  • Surgical Complications

Background:

  • Transurethral resection of the prostate (TURP) can lead to blood loss.
  • Disseminated intravascular coagulation (DIC) is a known complication contributing to post-TURP bleeding.
  • Absorption of prostatic substances can trigger DIC.

Purpose of the Study:

  • To determine if simple coagulation tests predict excessive bleeding post-TURP.
  • To assess the utility of prothrombin time (PT) and activated partial thromboplastin time (aPTT) in predicting post-operative hemorrhage.
  • To identify risk factors for significant bleeding after prostate surgery.

Main Methods:

  • Prospective study of 110 patients undergoing TURP.
  • Measurement of PT and aPTT immediately after surgery.

Related Experiment Videos

  • Definition and assessment of significant post-operative hemorrhage.
  • Correlation of coagulation test results with resected prostate weight and blood loss.

    • Main Results:

    • 34.5% of patients experienced significant post-operative bleeding.
    • 74% of bleeding patients had an abnormal PT (> or = 15 s) immediately post-surgery.
    • Abnormal PT predicted bleeding risk, independent of resected prostate weight.
    • Abnormal PT and aPTT occurred in 18% of patients, all with significant blood loss.
    • Patients with abnormal PT and resected weight >= 35g were identified as high-risk.

    Conclusions:

    • Simple coagulation tests, particularly PT, are valuable in predicting significant post-operative bleeding after TURP.
    • Abnormal PT and aPTT results can identify patients at high risk for hemorrhage.
    • Early post-operative coagulation screening can aid in managing bleeding risks in TURP patients.