Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Idiopathic slow-transit constipation

A MacDonald1, J N Baxter, I G Finlay

  • 1University Department of Surgery, Glasgow Royal Infirmary, UK.

The British Journal of Surgery
|September 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effects of anthropogenic sound on behaviour and physiology in female Port Jackson sharks Heterodontus portusjacksoni (Elasmobranchii).

Marine pollution bulletin·2025
Same author

Multicenter study on long-term growth in patients with phenylketonuria.

Orphanet journal of rare diseases·2025
Same author

Older Lineages of Vascular Plants in Wetlands Dominate in Habitats That Are More Ubiquitous Across the Region: A Case Study in Southern Africa.

Ecology and evolution·2025
Same author

Nutritional profiling of foods for Phenylketonuria.

Scientific reports·2025
Same author

European guidelines on diagnosis and treatment of phenylketonuria: First revision.

Molecular genetics and metabolism·2025
Same author

Dissolved organic matter quantity and quality response of tropical rainforest headwater rivers to the transition from dry to wet season.

Scientific reports·2024
Same journal

Trimester-Specific Safety of Laparoscopic versus Open Abdominal Surgery During Pregnancy: A Systematic Review and Meta-analysis.

The British journal of surgery·2026
Same journal

The Gut Microbiome in Surgical Oncology: Mechanisms, Perioperative Outcomes, and Therapeutic Opportunities.

The British journal of surgery·2026
Same journal

Patient-led, home-based follow-up for colorectal cancer: the DISTANCE multicentre stepped-wedge cluster-randomised trial.

The British journal of surgery·2026
Same journal

Correction to: Reduced secretory efficiency in parathyroid carcinoma: diagnostic value of the PTH-to-tumour-volume ratio.

The British journal of surgery·2026
Same journal

Global disparities in hepatocellular carcinoma outcomes: multicentre study.

The British journal of surgery·2026
Same journal

Surgical Outcomes from Nationwide Implementation of the International Best-Practice for Locally Advanced Pancreatic Cancer (PREOPANC-4) study.

The British journal of surgery·2026
See all related articles

Surgical management for slow-transit constipation, primarily colectomy, is being re-evaluated. New insights into the colon

Area of Science:

  • Gastroenterology and Colorectal Surgery

Background:

  • Idiopathic slow-transit constipation (STC) management historically relied on colectomy.
  • Colectomy and ileorectal anastomosis, while effective for many, can lead to persistent or worsened symptoms in some STC patients.

Purpose of the Study:

  • To question the universal rationale of colectomy for all severe constipation cases.
  • To explore current understanding of STC aetiology, investigation, neuropathology, and surgical outcomes.

Main Methods:

  • Review of recent observations on STC aetiology.
  • Analysis of clinical investigations in STC.
  • Examination of neuropathological findings in STC.
  • Evaluation of surgical outcomes for STC.

Main Results:

Related Experiment Videos

  • The colon is increasingly recognized as a critical area in health and disease.
  • Persistent or worsened symptoms post-colectomy suggest limitations in current surgical approaches for STC.

Conclusions:

  • The established surgical approach of colectomy for severe constipation warrants re-evaluation.
  • Further research into STC's underlying mechanisms is needed to refine treatment strategies.