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Racemization of aspartic acid in the extracellular matrix proteins of primary and secondary dentin
1Hebrew University Hadassah School of Dental Medicine, Jerusalem, Israel.
Abstract:
The accumulation with age of D-aspartic acid in primary and secondary human dentin was determined. In primary dentin, the plot of the D/L Asp ratio vs. age was found to fit first-order kinetics in accordance with the literature. But the secondary dentin behaved in an irregular manner and showed, in the great majority of cases, significantly increased D/L Asp ratios. Possible reasons for these findings, such as differences in protein composition and/or in the prevailing temperature, are discussed.
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