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Mapping of the chromosome 11 breakpoint of the t(4;11)(q21;p14-15) translocation
V Kalatzis1, G B Peters, A Dobrovic
1Department of Haematology/Oncology, Queen Elizabeth Hospital, Woodville, South Australia.
Cancer Genetics and Cytogenetics
|September 1, 1993
Abstract:
We describe the localization of the chromosome 11 breakpoint of a T-ALL translocation, t(4;11)(q21;p14-15), to sub-band 11p15.5. The breakpoint is located between the genes for insulin-like growth factor II (IGFII) and the M1 subunit of ribonucleotide reductase (RRM1). This region does not include any previously cloned genes involved in cancer.