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Trisomy 4 may occur in a broad range of hematologic malignancies
1Haematology Section, University Department of Pathology, Queen Mary Hospital, Hong Kong.
Cancer Genetics and Cytogenetics
|September 1, 1993
Abstract:
Trisomy 4 is an uncommon numerical chromosomal aberration in acute leukemia. We describe three cases of trisomy 4, occurring in two patients with acute myeloid leukemia (M1 and M5a) and in one patient with T-cell acute lymphoblastic leukemia. Our results suggest that trisomy 4 may occur in a broader range of hematologic and malignancies than previously described.