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A complex translocation, t(4;11;13)(q21;q23;q12-14), in a case of infantile acute lymphoblastic leukemia
A T Matsunaga1, H Torfi, J Feusner
1Department of Hematology-Oncology, Oakland Children's Hospital, CA 94609.
Cancer Genetics and Cytogenetics
|September 1, 1993
Abstract:
Cytogenetic analysis provides valuable prognostic information in children diagnosed with hematologic malignancies. While the t(4;11)(q21;q23) has frequently been reported in patients with acute lymphoblastic leukemia, the additional involvement of chromosome 13 to form a three-way translocation has not been described previously. We report a case of acute lymphoblastic leukemia in a 5-month old infant with a complex t(4;11;13)(q21;q23;q12-14).