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Cancer incidence differences between ethnic groups in Surinam
1Pathologisch Laboratorium, Academisch Ziekenhuis, Anton de Kom Universiteit, Paramaribo, Surinam.
Malignant disease patterns in Surinam varied significantly across ethnic groups, with cervical cancer common in females. Genetic susceptibility likely influences these cancer variations.
Area of Science:
- Epidemiology
- Oncology
- Medical Genetics
Background:
- Centralized cancer registration in Surinam enabled a comprehensive study of malignant diseases.
- The study period spanned twelve years, from 1979 to 1990, covering all new pathology-confirmed cases.
- Patient data were analyzed based on demographics like sex, age, and ethnicity, alongside primary cancer site.
Purpose of the Study:
- To investigate the incidence and distribution of malignant diseases in Surinam.
- To identify variations in cancer rates among different racial and ethnic groups.
- To explore potential contributing factors, including genetic susceptibility, to observed cancer disparities.
Main Methods:
- Utilized data from a central cancer registry for pathology-confirmed cases.
- Categorized patients by sex, age, racial/ethnic background, and primary site of malignancy.
- Performed proportional rate analysis for general malignancy and specific cancer types across ethnic groups.
Main Results:
- A predominance of female patients was observed, primarily due to a high incidence of cervical cancer.
- Significant differences in the proportional rates of overall malignancy and the four most common cancer types were noted among various ethnic groups.
- The findings suggest a complex interplay of factors contributing to cancer incidence in Surinam.
Conclusions:
- Ethnic variations in malignant disease patterns are evident in Surinam.
- Genetic factors are presumed to play a substantial role in the observed differences in cancer susceptibility.
- Further research into the genetic epidemiology of cancer in Surinam is warranted.
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