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Related Experiment Video

Updated: Jul 6, 2026

Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights

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Published on: October 13, 2023

Widespread syringomata in Down's syndrome

L E Rhodes¹, J L Verbov

¹Department of Dermatology, Royal Liverpool University Hospital, UK.

Clinical and Experimental Dermatology

|July 1, 1993

Summary

This case study describes widespread syringomata in a woman with Down's syndrome. While periorbital syringomata are common in Down syndrome, extensive cases are rare, highlighting a need for further research.

Area of Science:

Dermatology
Clinical Genetics

Background:

Down syndrome is a genetic disorder associated with various dermatological conditions.
Syringomata, benign tumors of the sweat glands, are frequently observed around the eyes in individuals with Down syndrome.

Observation:

This report details a rare case of extensive syringomata affecting a broader area of the skin in a woman diagnosed with Down syndrome.
The distribution of syringomata extended beyond the typical periorbital region.

Findings:

The case presents a rare manifestation of syringomata in an individual with Down syndrome.
This occurrence is unusual given the typically localized periorbital presentation.

Implications:

This case expands the known spectrum of dermatological manifestations in Down syndrome.

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Further investigation into the genetic and clinical factors underlying widespread syringomata in Down syndrome is warranted.