Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fatal facial ulceration

R H Bull1, R A Marsden, M G Cook

  • 1Department of Dermatology, St George's Hospital, London, UK.

Clinical and Experimental Dermatology
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Melanoma predilection for the lower limbs of women compared with men.

Archives of dermatological research·2022
Same author

Erythrodermic pustular psoriasis triggered by intravesical bacillus Calmette-Guérin immunotherapy.

Clinical and experimental dermatology·2012
Same author

A difficult diagnosis: drug-induced subacute cutaneous lupus erythematosus (SCLE) triggered by omeprazole in a patient with pre-existing idiopathic SCLE.

Clinical and experimental dermatology·2012
Same author

Doping of carbon nanotubes with nitrogen improves protein coverage whilst retaining correct conformation.

Nanotechnology·2011
Same author

Longitudinal photocurrent spectroscopy of a single GaAs/AlGaAs v-groove quantum wire.

Nanotechnology·2011
Same author

Photoaggravated Sweet's syndrome.

Clinical and experimental dermatology·2010

Wegener's granulomatosis can be difficult to diagnose, particularly in its limited form. This case highlights diagnostic challenges, with confirmation only occurring post-mortem.

Area of Science:

  • Rheumatology
  • Pathology
  • Dermatology

Background:

  • Wegener's granulomatosis is a rare autoimmune disease characterized by granulomatous inflammation.
  • Diagnosis can be challenging, especially in limited cutaneous or localized forms.
  • Early diagnosis is crucial for effective treatment and improved patient outcomes.

Observation:

  • An elderly male presented with a large facial ulcer.
  • Clinical presentation did not immediately suggest systemic vasculitis.
  • Diagnostic workup was complicated by the localized nature of the initial symptoms.

Findings:

  • Post-mortem examination revealed granulomatous vasculitis affecting both skin and lungs.
  • Histopathological findings confirmed Wegener's granulomatosis.

Related Experiment Videos

  • The case exemplifies the 'limited' or localized presentation of the disease.

    • Implications:

    • This case underscores the diagnostic difficulties associated with limited Wegener's granulomatosis.
    • Highlights the importance of considering vasculitis in unexplained ulcerative lesions.
    • Emphasizes the need for thorough investigation, even in seemingly localized presentations.