[Histopathologic analysis of mullerian adenocarcinomas]

A histopathologic review of 959 cases of the endocervical, endometrial and tubal adenocarcinomas is presented. Most of the histopathologic types of the adenocarcinoma in each site were in consistent with that of it's native epithelium, which were 43.7%, 74.5% and 85.5%, respectively. However, other types besides native type may be found in any site adenocarcinoma. The pathologic features of the surroundings in some early lesions demonstrated a possible different morphogenesis. The synchronous multiple site primary adenocarcinomas in the mullerian system were common, comprising 7.8%, in which were composed of 91% in 2 sites, 7.5% in 3 sites, and 1.5% in 4 sites. Most of them were endometrial and ovarian adenocarcinomas, in 37.3%. These data suggested the complex histopathologic types of the mullerian adenocarcinomas including the endocervical, endometrial and tubal adenocarcinomas should be considered before diagnoses, especially in biopsy specimens. The synchronous multiple site primary adenocarcinomas were not rare for the same origin of histogenesis. Thus, a correct diagnosis will be conductive to stage and management.