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[Effect of ligustrazine controlled release capsule on hemorrheology in patients with cor pulmonale]
1Respiratory Disease Research Institute, Tongji Hospital, Tongji Medical University, Wuhan.
Zhonghua Nei Ke Za Zhi
|January 1, 1993
Abstract:
Before and after oral administration of Ligustrazine controlled release capsule, changes of hemorrheology and TXA2/PGI2 were evaluated in 16 patients with advanced cor pulmonale. It was shown that the effects of decreasing whole blood and plasma viscosity and lowering hematocrit and fibrinogen level were noted after one course of treatment with this medication. It is suggests that anticoagulant, effect of Ligustrazine is probably related to its role of improving inbalance between TXA2 and PGI2 in patients with cor pulmonale.