Related Experiment Video
Updated: May 8, 2026
11:30
Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
Published on: August 26, 2011
Selective affective biasing in recognition memory in the irritable bowel syndrome
J E Gomborone1, P A Dewsnap, G W Libby
1Department of Gastroenterology, St Bartholomew's Hospital, London.
Gut
|September 1, 1993
Summary
Irritable bowel syndrome (IBS) patients exhibit a negative cognitive bias, similar to depressed patients. IBS patients also show a unique bias for negative information, potentially impacting their self-perception.
Area of Science:
- Cognitive Psychology
- Gastroenterology
- Clinical Psychology
Background:
- Depression is linked to biased information processing.
- The cognitive relationship between depression and Irritable Bowel Syndrome (IBS) requires further exploration.
Purpose of the Study:
- To investigate the cognitive processing of emotional information in IBS patients.
- To compare cognitive biases in IBS patients with those in depressed patients, patients with organic gastrointestinal disease, and healthy controls.
Main Methods:
- A word recognition memory task was employed, using positive, neutral, and negative stimulus words.
- Four age-matched groups were studied: IBS patients, depressed patients, patients with organic gastrointestinal disease, and healthy volunteers.
Main Results:
- Depressed patients demonstrated a significant bias towards negative words.
- IBS patients exhibited a similar negative bias.
- IBS patients made more false-positive errors for negative words compared to depressed patients and healthy volunteers, indicating a confirmatory bias for negative material.
Conclusions:
- IBS patients display a negative cognitive bias and a specific confirmatory bias for negative information.
- This cognitive pattern may influence how IBS patients interpret their own bodily sensations.
- Findings suggest a cognitive link between IBS and depression, warranting further clinical investigation.
More Related Videos
Related Concept Videos
01:17Chronic Bowel Disorders: Introduction
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
01:17Drugs for Treatment of Diarrhea-Predominant IBS
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
01:17Irritable Bowel Syndrome I: Introduction
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
01:30Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
01:30Irritable Bowel Syndrome III: Medical and Nursing Management
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
01:23Irritable Bowel Syndrome
DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility PatternsDisordered...