Tarsal tunnel syndrome secondary to cosmetic silicone injections

Silicone has been implicated as a cause of inflammatory disorders in the body including synovitis and lymphangitis. Silicone particulate matter has been shown to cause a fairly severe chronic foreign body reaction with the use of silicone prosthesis in the foot. This reaction was often overlooked for years because of the limited number of subjective complaints. There are case reports of granulomatous inguinal lymphadenopathy following first metatarsophalangeal joint silicone arthroplasty. Similar findings have been noted in the axilla with hand implants and breast implants. Of greater significance are two reports of malignant lymphoma found with silicate lymphadenopathy.