Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Repeat hepatic resection for recurrent hepatocellular carcinoma

T Kakazu1, M Makuuchi, S Kawasaki

  • 1First Department of Surgery, Shinshu University, School of Medicine, Matsumoto, Japan.

Hepato-Gastroenterology
|August 1, 1993
PubMed
Summary

Repeat hepatectomy is a safe and effective option for patients with recurrent hepatocellular carcinoma (HCC) whose liver function remains stable. This procedure offers significant long-term survival benefits for eligible patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Coffin-Siris syndrome].

Ryoikibetsu shokogun shirizu·2001
Same author

Transcriptional regulation of the murine acetyl-CoA synthetase 1 gene through multiple clustered binding sites for sterol regulatory element-binding proteins and a single neighboring site for Sp1.

The Journal of biological chemistry·2001
Same author

Outbreak of enterohemorrhagic Escherichia coli O157 mass infection caused by "whole roasted cow".

Japanese journal of infectious diseases·2001
Same author

Observation of a soft smectic liquid-crystal phase in a mixture showing V-shaped switching.

Physical review. E, Statistical, nonlinear, and soft matter physics·2001
Same author

Observation of a pretransitional effect near a virtual smectic-A--smectic-C* transition.

Physical review. E, Statistical, nonlinear, and soft matter physics·2001
Same author

[Surgical treatment of liver metastases from colorectal cancer patient selection and oncological outcome].

Nihon Geka Gakkai zasshi·2001

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Gastroenterology

Background:

  • Hepatocellular carcinoma (HCC) frequently recurs after initial treatment.
  • Liver resection is a primary curative treatment for HCC, but recurrence rates are high.

Purpose of the Study:

  • To evaluate the safety and efficacy of repeat hepatectomy for recurrent HCC.
  • To assess long-term survival outcomes following repeat liver resections.

Main Methods:

  • Retrospective analysis of 268 patients undergoing initial hepatic resection for HCC over 12 years.
  • Evaluation of indications for repeat hepatectomy mirroring criteria for the first operation.
  • Detailed follow-up of patients who underwent second or third hepatic resections.

Related Experiment Videos

Main Results:

  • 78% of patients experienced tumor recurrence within 5 years post-initial resection.
  • 24 patients underwent repeat hepatectomy (18 second, 6 third) with no operative mortality.
  • Cumulative survival rates after first hepatectomy were 87.1% at 3 and 5 years, and 72.6% at 7 years for repeat resection patients.

Conclusions:

  • Repeat hepatectomy is a safe and viable treatment option for recurrent HCC.
  • Patients with stable liver function post-initial resection benefit significantly from repeat hepatectomy.
  • This approach can achieve favorable long-term survival in selected HCC patients.