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An 88-kilodalton antigen secreted by Aspergillus fumigatus
H Kobayashi1, J P Debeaupuis, J P Bouchara
1Unité de Mycologie, Institut Pasteur, Paris, France.
Infection and Immunity
|November 1, 1993
Abstract:
An 88-kDa component secreted in vitro by Aspergillus fumigatus has been purified by sequential chromatographic procedures. The molecule is a glycoprotein with an N-linked sugar moiety composed of mannose glucose, and galactose (16:10:1). It is recognized by antibodies from patients with aspergilloma and has potential for the immunodiagnosis of aspergilloma. The antigenicity is associated with the polypeptide part of the molecule (79 kDa).