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Histoplasmosis in horses

G B Rezabek1, J M Donahue, R C Giles

  • 1Department of Veterinary Science, College of Agriculture, University of Kentucky, Lexington 40511.

Journal of Comparative Pathology
|July 1, 1993
PubMed
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Histoplasmosis, a fungal infection caused by Histoplasma capsulatum, led to severe health issues in horses. This included abortions, fatal pneumonia in foals, and lymphadenitis in a weanling.

Area of Science:

  • Veterinary Medicine
  • Mycology
  • Equine Health

Background:

  • Histoplasmosis is a systemic fungal infection caused by Histoplasma capsulatum.
  • While known to affect various mammals, its impact on equine reproductive and neonatal health requires further understanding.

Purpose of the Study:

  • To document and analyze cases of histoplasmosis in horses.
  • To describe the clinical manifestations and outcomes of Histoplasma capsulatum infection in equine populations.

Main Methods:

  • Retrospective case review of equine patients diagnosed with histoplasmosis between 1986 and 1990.
  • Clinical data including symptoms, diagnostic findings, and outcomes were analyzed.

Main Results:

  • Nine horses were diagnosed with histoplasmosis during the study period.

Related Experiment Videos

  • Infections resulted in granulomatous placentitis and abortion in four mares.
  • Severe granulomatous pneumonia caused death in four newborn foals within days of birth.
  • A five-month-old weanling developed granulomatous pneumonia and lymphadenitis.

    • Conclusions:

    • Histoplasma capsulatum poses a significant threat to equine health, particularly affecting pregnant mares and foals.
    • The study highlights the potential for severe reproductive and respiratory complications in horses due to histoplasmosis.