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Microcystic adnexal carcinoma
T S Sebastien1, B R Nelson, L Lowe
1Department of Dermatology, University of Michigan Medical Center, Ann Arbor 48109.
Journal of the American Academy of Dermatology
|November 1, 1993
Summary
Microcystic adnexal carcinoma is a rare skin cancer with aggressive local growth, high rates of perineural invasion, and recurrence. This report details two cases and reviews current management strategies for this challenging neoplasm.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Microcystic adnexal carcinoma (MAC) is a rare, aggressive skin neoplasm.
- Characterized by invasive, relentless, and destructive local growth.
- High incidence of perineural invasion and tumor recurrence.
Observation:
- Presents two cases of MAC with typical clinical features.
- Details the use of formalin-fixed, paraffin-embedded horizontal Mohs sections in one case.
- Highlights the diagnostic and therapeutic challenges posed by MAC.
Findings:
- Confirms the aggressive nature of MAC.
- Illustrates the utility of specific histopathological techniques in diagnosis.
- Emphasizes the importance of complete surgical excision and surveillance.
Implications:
- Informs clinicians about the challenging nature of MAC.
- Suggests potential improvements in diagnostic methods.
- Underscores the need for comprehensive management strategies to improve patient outcomes.