Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Relapsing syphilis

J Yoon1, I B Haam, K Y Chung

  • 1Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.

The Journal of Dermatology
|July 1, 1993
PubMed
Summary

Benzathine penicillin treatment failure in secondary syphilis was observed. This case suggests potential inadequacy of current penicillin regimens for early syphilis, necessitating further investigation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Multi-Center Study on eFAST Learning Curves for Emergency Medicine Residents Using CUSUM Analysis.

AEM education and training·2026
Same author

Microfluidics meets organoids: Kidney and bladder-on-Chip models for preclinical drug delivery assessment.

Advanced drug delivery reviews·2026
Same author

Corrigendum to 'Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer': [ESMO Open. Volume 11, Issue 2, February 2026, 106057].

ESMO open·2026
Same author

Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer.

ESMO open·2026
Same author

A GPS-based investigation into the relationship between exercise irregularity and osteochondritis dissecans in Thoroughbred weanlings: A case-control study.

Veterinary journal (London, England : 1997)·2025
Same author

Exploring the effects of exercise on T cell function and metabolism in cancer: a scoping review protocol.

Frontiers in physiology·2025

Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Public Health

Background:

  • Penicillin remains a primary treatment for syphilis.
  • Concerns exist regarding the efficacy of current penicillin regimens for early syphilis.
  • Benzathine penicillin is a common treatment for syphilis.

Observation:

  • A case of secondary syphilis treated with benzathine penicillin experienced treatment failure.
  • The patient showed signs of relapse after initial treatment.
  • Thorough contact tracing did not reveal any reinfection sources.

Findings:

  • This case highlights a potential treatment failure of benzathine penicillin in secondary syphilis.
  • The relapse suggests that the administered penicillin regimen may have been inadequate.
  • The findings challenge the universal effectiveness of current standard treatments.

Implications:

  • Further research is needed to evaluate the effectiveness of current syphilis treatment protocols.
  • Alternative or augmented treatment strategies may be required for early syphilis.
  • This case underscores the importance of monitoring treatment outcomes and considering antimicrobial resistance in syphilis management.

Related Experiment Videos