Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Deep hypothermic arrest: observations on later development in children

J S Wright, R G Hicks, D C Newman

    The Journal of Thoracic and Cardiovascular Surgery
    |March 1, 1979
    PubMed
    Summary

    Children undergoing ventricular septal defect repair in infancy showed developmental differences. Deep hypothermic arrest was associated with a higher incidence of developmental abnormality compared to continuous perfusion methods.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Rupture of intestines by blows upon abdomen.

    Canadian Medical Association journal·2010
    Same author

    The Sociologic and Economic Aspects of Tuberculosis.

    Canadian Medical Association journal·2010
    Same author

    Evaluation of a bioabsorable polylactide film in a large animal model for the reduction of retrosternal adhesions.

    The Journal of surgical research·2004
    Same author

    Subtelomeric deletion of 18p in an adult with paranoid schizophrenia and mental retardation.

    American journal of medical genetics. Part A·2004
    Same author

    Weak magnetic coupling of coordinated verdazyl radicals through diamagnetic metal ions. Synthesis, structure, and magnetism of a homoleptic copper(I) complex.

    Inorganic chemistry·2001
    Same author

    Synthesis, structure, and magnetism of bimetallic manganese or nickel complexes of a bridging verdazyl radical.

    Inorganic chemistry·2001

    Area of Science:

    • Pediatric Cardiac Surgery
    • Developmental Pediatrics
    • Cardiovascular Research

    Background:

    • Ventricular septal defect (VSD) is a common congenital heart defect.
    • Surgical closure of VSD in infancy is standard practice.
    • Different cardiopulmonary bypass techniques may impact neurodevelopmental outcomes.

    Purpose of the Study:

    • To compare neurodevelopmental outcomes in infants undergoing VSD closure.
    • To evaluate the impact of two distinct cardiopulmonary bypass methods on child development.

    Main Methods:

    • Retrospective review of 32 children following VSD closure in infancy.
    • Comparison between 15 patients who underwent continuous perfusion and 17 who had deep hypothermic arrest.
    • Neurodevelopmental assessment (intellectual and motor) between 7 and 72 months post-operation via parental and professional evaluations.

    Related Experiment Videos

    Main Results:

    • A higher incidence of developmental abnormality was observed in the subgroup treated with deep hypothermic arrest.
    • Neurodevelopmental assessments indicated potential differences between the two surgical approaches.
    • Outcomes were evaluated over a long-term follow-up period.

    Conclusions:

    • Deep hypothermic arrest may be associated with an increased risk of developmental abnormalities after infant VSD repair.
    • Continuous perfusion might be a safer alternative regarding neurodevelopmental outcomes.
    • Further research is warranted to confirm these findings and optimize surgical strategies.