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Related Experiment Videos

Relationship between zinc and obesity

G Di Martino1, M G Matera, B De Martino

  • 1Department of Clinical Methodology, Faculty of Medicine and Surgery, Second University of Naples, Italy.

Journal of Medicine
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

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Obese individuals often have lower serum zinc levels. A severe hypocaloric diet normalized zinc levels and body mass index (BMI), suggesting a link between zinc and obesity metabolism.

Area of Science:

  • Nutrition Science
  • Metabolic Disorders
  • Human Physiology

Background:

  • Zinc plays a crucial role in metabolic processes and thermoregulation, particularly in obese individuals.
  • Obesity is often associated with altered metabolic profiles and potential micronutrient deficiencies.

Purpose of the Study:

  • To investigate serum zinc levels in obese patients before and after a severe hypocaloric diet.
  • To assess the correlation between serum zinc levels and body mass index (BMI) in this cohort.

Main Methods:

  • A cohort of obese patients underwent a 60-day severe hypocaloric diet (737 Kcal).
  • Serum zinc (Zn) levels and body mass index (BMI) were measured pre- and post-intervention.

Main Results:

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  • Obese patients exhibited significantly lower serum zinc levels (p < 0.01) compared to controls.
  • A significant elevation in BMI was observed in the obese group compared to controls.
  • Following the hypocaloric diet, both serum zinc and BMI levels returned to normal ranges.

    • Conclusions:

    • Serum zinc levels appear to be related to anabolic and catabolic mechanisms in obesity.
    • Dietary interventions may influence zinc status in obese individuals.
    • The precise metabolic function of zinc in obesity warrants further investigation.