Related Experiment Video
Updated: Oct 6, 2026

09:43
Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
A clinico-pathological study of adult histiocytosis X involving the brain
1Department of Neurology, Kitasato University School of Medicine, Kanagawa, Japan.
Journal of Neurology, Neurosurgery, and Psychiatry
|September 1, 1993
Abstract:
Adult histiocytosis X involving the CNS caused progressive spastic paraparesis. The diagnosis was made by immunoreactive anti-S100 protein antibody staining and from the presence of Birbeck granules in biopsy specimens of skin lesions. Neuropathological examination showed massive proliferation and infiltration of S-100 containing histiocyte-like cells and reactive astrocytes throughout the CNS.

