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Head and neck synovial sarcomas

S Pai1, R F Chinoy, S A Pradhan

  • 1Department of Pathology, Tata Memorial Hospital, Bombay, India.

Journal of Surgical Oncology
|October 1, 1993
PubMed
Summary
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Synovial sarcoma of the head and neck is rare, presenting as a mass. Diagnosis requires advanced techniques, and while surgery is primary, outcomes vary, emphasizing the need for accurate histology.

Area of Science:

  • Oncology
  • Head and Neck Surgery
  • Pathology

Background:

  • Synovial sarcoma is a rare soft tissue tumor.
  • Head and neck presentation is uncommon, often presenting as a palpable mass.
  • Accurate histopathological diagnosis is crucial for appropriate management.

Purpose of the Study:

  • To analyze cases of synovial sarcoma in the head and neck region.
  • To highlight the histopathological differential diagnosis for this rare tumor.
  • To contribute data on the clinical presentation, treatment, and outcomes.

Main Methods:

  • Retrospective analysis of eleven head and neck synovial sarcoma cases.
  • Histopathological examination, including immunohistochemistry and electron microscopy for variant identification.

Related Experiment Videos

  • Review of treatment modalities, primarily radical surgery and adjuvant radiotherapy.

    • Main Results:

    • Tumors ranged from 3 to 8 cm, located in the parapharynx, pharyngeal wall, or nape of the neck.
    • Ten cases showed a classic biphasic pattern; one monophasic variant was diagnosed using advanced techniques.
    • Five patients died of disease, while six survived for 9 months to 15 years post-treatment.

    Conclusions:

    • Synovial sarcoma of the head and neck requires careful histopathological evaluation, differentiating it from carcinomas and other sarcomas.
    • Radical surgery combined with radiotherapy for residual disease is the primary treatment approach.
    • Outcomes for head and neck synovial sarcoma are variable, underscoring the importance of early and accurate diagnosis.