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Ketamine anesthesia for short transurethral urologic procedures
M M Attalah1, M M Saied, R Yahya
1Urology and Nephrology Center, Univ. of Mansoura, Egypt.
Middle East Journal of Anaesthesiology
|June 1, 1993
Summary
Ketamine provides effective anesthesia for short procedures. Midazolam aided smooth recovery, while methylphenidate did not improve recovery and increased adverse effects in patients receiving ketamine anesthesia.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Ketamine is a valuable anesthetic but has limitations like cardiovascular effects and emergence reactions.
- Midazolam and methylphenidate have been explored to mitigate ketamine's side effects and improve recovery.
Purpose of the Study:
- To evaluate the efficacy of midazolam and methylphenidate, alone and in combination, for improving recovery from ketamine anesthesia during short urologic procedures.
Main Methods:
- A double-blind study involving 30 patients undergoing transurethral urologic procedures.
- Patients were randomized into three groups receiving ketamine with either midazolam, methylphenidate, or both.
- Perioperative monitoring included cardiovascular parameters and plasma catecholamines; recovery was assessed using a triad visual analog scale.
Main Results:
- Ketamine provided satisfactory anesthesia.
- Midazolam addition did not alter cardiovascular responses but facilitated smoother recovery without affecting recovery scores.
- Methylphenidate did not improve recovery scores and was associated with increased vomiting, excessive talking, and limb movements.
Conclusions:
- Midazolam can be used with ketamine to ensure smooth recovery from anesthesia for short urologic procedures.
- Methylphenidate is not recommended for improving ketamine recovery due to increased adverse events.