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[Hemoglobin SD disease]

H J Laws1, R Dickerhoff, J Mayer

  • 1Zentrum für Kinder- und Jugendmedizin, Kreiskrankenhaus Lüdenscheid.

Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
|September 1, 1993
PubMed
Summary
This summary is machine-generated.

A rare case of severe Hemoglobin SD disease caused a cerebral infarction in a child after a blood transfusion. Early diagnosis and long-term transfusions are key for managing this condition.

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Area of Science:

  • Hematology
  • Pediatrics
  • Neurology

Background:

  • Sickle cell disease and hemoglobinopathies are inherited blood disorders.
  • Hemoglobin SD disease is a rare variant typically presenting with mild symptoms.

Observation:

  • A 7-year-old girl developed cerebral infarction and hemiparesis post-blood transfusion.
  • Blood film suggested sickle cell anemia, but electrophoresis revealed Hemoglobin S and D.

Findings:

  • The patient was diagnosed with Hemoglobin SD disease, a typically mild condition.
  • This case represents a severe, previously unreported manifestation of Hemoglobin SD disease.

Implications:

  • Highlights the potential for severe complications in rare hemoglobinopathies.
  • Emphasizes the need for prompt diagnosis and management strategies, including transfusion programs, to prevent recurrent events.