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Interictal heart rate patterns in partial seizure disorders
R C Frysinger1, J Engel, R M Harper
1Department of Anatomy and Cell Biology, UCLA School of Medicine 90024-1763.
Neurology
|October 1, 1993
Abstract:
Epileptogenic mesial temporal damage may alter interictal autonomic patterning. Analysis of heart rate variability in 19 patients with complex partial seizures revealed cases of persistent, high-amplitude, 4 to 9 per minute fluctuations in heart rate during alert waking. This pattern was most pronounced in poor candidates for anterior temporal lobe resection (2/19). The 4 to 9 per minute heart-rate variability pattern may emerge following diffuse, extratemporal, or bilateral mesial temporal damage, which interferes with descending forebrain influences on cardiovascular regulation.